COVID-19
Supplements studied for COVID-19.
Overview
Supplement research for COVID-19 remains mixed, with the strongest signals for Vitamin D and Zinc (DEX Score 68; medium effect size, high evidence, high trust). Low vitamin D appears linked to greater infection and severity risk, and supplementation may help people who start deficient, including some hospitalized patients. Vitamin C (15 studies) shows very low effect size despite medium evidence; oral high doses did not clearly speed recovery in outpatients, and IV use in hospital usually did not improve outcomes.
Melatonin and N-Acetyl Cysteine (NAC) have low-trust evidence. Early melatonin studies suggest possible severity benefits, but results conflict. IV NAC did not clearly help severe cases, while one small oral study reported possible benefit. See the heatmap and evidence reviews below for condition-by-condition detail.
Effect graph
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Relevant supplements heatmap
Relevant supplements sorted by DEX Score.
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See effect size, evidence strength, and trust at a glance for every condition.
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SupplementDEX Database
17 supplements for , and rated at least stars. All purchase bands. No minimum star filter.
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Evidence visualised
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Visual summaries of supplement evidence ranked by condition.
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