Cachexia
Supplements studied for cachexia.
Overview
Cachexia research here spans four supplements with uneven evidence. L-Carnitine has three studies suggesting it may increase body mass index in cancer-related wasting at 4 g daily over 12 weeks, and may add benefit when combined with other agents in combination trials.
Branched Chain Amino Acids (BCAAs) show promise in small studies for appetite and nutritional markers in wasting linked to cancer, liver disease, or dialysis, though many lacked strong comparators. Melatonin 20 mg nightly did not improve appetite or body composition in one advanced-cancer trial. Fish Oil has six listed studies but no detailed summary is available. See the heatmap and evidence reviews below.
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