SupplementDEX

Polycystic ovary syndrome (PCOS)

Supplements studied for polycystic ovary syndrome (PCOS).

Overview

Inositol (DEX Score 88; high effect size, very high evidence, very high trust) has high-strength evidence for PCOS, with 25 studies showing it may modestly reduce weight, blood sugar, cholesterol, and androgen levels and increase ovulation rates, though pregnancy outcomes are less clear and it may be less effective than metformin for some measures. N-Acetyl Cysteine (NAC) (DEX Score 68; medium effect size, very high evidence, medium trust) may improve ovulation and insulin resistance but is generally less effective than metformin.

Berberine (DEX Score 72; medium effect size, high evidence, very high trust) and L-Carnitine (DEX Score 72; medium effect size, high evidence, very high trust) may improve metabolic and fertility-related outcomes in some trials. Resveratrol (DEX Score 72; medium effect size, high evidence, very high trust) has inconsistent results across studies. See the heatmap and evidence reviews below.

Effect graph

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SupplementDEX Database

24 supplements for , , and rated at least stars. All purchase bands. No minimum star filter.

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