Studies in SupplementDEX Database:
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Conditions for Creatine
- Clinical conditions covered:603
- Supplements in the database:152
- Practitioner summaries written:
2,6662,666 - Patient-friendly summaries written:
2,6662,666 - PubMed citations linked:
8,2678,267
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Dr Philip Nguyen (MBBS)
Thoracic Physician
SupplementDEX gives me peace of mind that my patients are receiving the best information on supplements
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Only 15% of supplements are recommended according to the DEX Score. Dig deeper with patient-friendly and detailed practitioner summaries for each data point.
Caffeine · Athletic performance (67 studies)
- Taking caffeine prior to exercise or sport can reliably improve athletic performance, endurance and strength in most people. The relative benefit is dependent on various individual factors including body weight and how often one consumes caffeine on a regular basis.
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Patient complaint
Top matches
#1 match
St. John's Wort
28 studies · Proven
88%
DEX Score
Proven evidence
#2 match
Acetyl-L-Carnitine
4 studies · Consider
72%
DEX Score
Consider evidence
#3 match
SAMe
8 studies · Consider
72%
DEX Score
Consider evidence
#4 match
Zinc
8 studies · Consider
72%
DEX Score
Consider evidence
#5 match
Curcumin
10 studies · Consider
68%
DEX Score
Consider evidence
1 of 5 · 42 total for Depression
Skip the PubMed rabbit hole. Human-reviewed summaries of the best RCTs.
28 studies indexed
Continuation and long-term maintenance treatmen…
2008
n=5,570
St John's wort for major depression
2008
n=5,489
Clinical use of Hypericum perforatum (St John's…
2017
n=3,808
+25 more · 14 RCT · 9 Meta · 2 Review
Hours of PubMed — before clinic
- St. John's wort (Hypericum perforatum) is considered effective for mild to moderate major depressive disorder, with e…
- Response rates in the short term range from 65% to 100%, with long-term response estimated between 60% and 69%.
- It appears to improve mood, anxiety, somatic symptoms, and insomnia associated with depression and generally causes f…
- Most clinical trials have tested specific standardized extracts containing 0.2-0.3% hypericin and/or 5-6% hyperforin…
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St. John's Wort · Depression
88%
DEX Score
Consider purchase
Effect size
High
Evidence
Very High
Trust
Very High
Trace every claim to the research. Study trails with effect sizes and PubMed links.
Practitioner Evidence Review
St. John's wort (Hypericum perforatum) is considered effective for mild to moderate major depressive disorder, with evidence from moderat…1
Clinical use of Hypericum perforatum (St John's wort) in depression: A…
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St. John's wort (Hypericum perforatum) is considered effective for mild to moderate major depressive disorder, with evidence from moderate-quality meta-analyses and clinical trials demonstrating superiority to placebo…
St. John's wort can be an effective option for mild to moderate depression, helping to lift mood, reduce anxiety, and improve sleep. Studies have shown that it works better than a placebo and can be as effective as some…