Primary Dysmenorrhea
Supplements studied for primary dysmenorrhea.
Overview
Vitamin E (5 studies) has the strongest evidence for primary dysmenorrhea, with trials showing that 200–500 IU daily starting two days before menstruation may reduce pain severity and duration. Vitamin D (3 studies) shows limited but consistent signals of modest pain relief across varying doses. Boron (1 study) may reduce pain and shorten duration when taken around the menstrual period, though evidence is preliminary.
See the heatmap and evidence reviews below for trial-level detail.
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