Peripheral arterial disease
Supplements studied for peripheral arterial disease.
Overview
L-Carnitine (WA 64; medium effect size, medium evidence, high trust) has medium-strength but mixed evidence for peripheral arterial disease. Taking 2 grams twice daily for three weeks may increase walking distance, but a single pre-exercise dose did not help, and adding L-carnitine to cilostazol showed no extra benefit. Cocoa (WA 44; low effect size, low evidence, medium trust) flavanol-rich drinks improved six-minute walk distance over six months in one PAD trial.
Garlic (WA 48; low effect size, medium evidence, medium trust) may modestly increase pain-free walking distance over 12 weeks. Alpha-Lipoic Acid (WA 32; very low effect size, low evidence, medium trust) may reduce exercise pain but not exercise duration. See the heatmap and evidence reviews below.
Effect graph
Relevant supplements
Relevant supplements sorted by DEX Score.
Studies
Find individual evidence reviews for supplements sorted by DEX Score.
5 supplements for , and rated at least stars. All purchase bands. No minimum star filter.
Evidence visualised
Same ratings as above, aggregated so you can see coverage and imbalance.