Peripheral neuropathy
Supplements studied for peripheral neuropathy.
Overview
St. John's Wort (WA 32; very low effect size, low evidence, medium trust) did not relieve peripheral neuropathy pain better than placebo in one small five-week trial. Vitamin B9 (Folate) (WA 36; low effect size, low evidence, very low trust) has unclear benefit—a combination product with B12 and uridine reduced pain by about 44% in an uncontrolled study, so the contribution of folic acid alone is unknown.
Overall supplement evidence for peripheral neuropathy is weak, with no supplement showing clear standalone benefit. Low and medium-low ratings reflect the sparse trial data.
The heatmap and evidence reviews below summarize available trials.
Effect graph
Relevant supplements
Relevant supplements sorted by DEX Score.
Studies
Find individual evidence reviews for supplements sorted by DEX Score.
2 supplements for rated at least stars. All purchase bands. No minimum star filter.
Evidence visualised
Same ratings as above, aggregated so you can see coverage and imbalance.