All-cause mortality
Supplements studied for all-cause mortality.
Overview
SupplementDEX indexes 18 supplements related to all-cause mortality across 63 studies, with mixed and often null findings for most adults.
Vitamin A (DEX Score 40; very low effect size, high evidence, medium trust) lowers death risk by roughly 12–26% in vitamin A–deficient children aged six months to five years and helps prevent serious illness, but does not reduce mortality in newborns or healthy adults. Potassium (DEX Score 64; medium effect size, medium evidence, high trust) shows uncertain links to longer life in observational research.
Vitamin C, Calcium, and Vitamin E supplements (DEX Score 40) generally do not reduce death risk; vitamin E supplements may slightly increase mortality in the best trials. See the heatmap and evidence reviews below for all indexed supplements.
Effect graph
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Relevant supplements heatmap
Relevant supplements sorted by DEX Score.
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SupplementDEX Database
18 supplements for and rated at least stars. All purchase bands. No minimum star filter.
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Evidence visualised
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Visual summaries of supplement evidence ranked by condition.
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