Acne
Supplements studied for acne.
Overview
SupplementDEX lists 18 supplements studied for acne across 40 trials. The strongest signals come from Zinc (WA 68; medium effect size, very high evidence, medium trust) and Aloe (WA 56; medium effect size, low evidence, medium trust). Oral zinc may modestly improve acne, though results vary and comparisons with standard acne medicines are unclear. Topical aloe gel added to routine care appeared to reduce pimples in one study.
Milk Thistle and Vitamin D carry lower ratings (WA 52). Milk thistle research is mixed: oral silymarin did not outperform doxycycline in a small trial, while some topical products showed moderate improvement in small studies. Vitamin D evidence remains uncertain, with one small study in people with low levels reporting reduced inflamed lesions.
N-Acetyl Cysteine (NAC) has only one low-rated study and is not well studied for acne. See the heatmap and evidence reviews below for full ratings across all supplements.
Relevant supplements
Relevant supplements sorted by DEX Score.
| Zinc | ★★★★★ | Medium |
| Aloe | ★★★★★ | Medium |
| Vitamin D | ★★★★★ | Low |
| Milk Thistle | ★★★★★ | Low |
| Vitamin B3 (Niacin) | ★★★★★ | Low |
| Green Tea | ★★★★★ | Low |
| Vitamin B2 (Riboflavin) | ★★★★★ | Low |
| Selenium | ★★★★★ | Low |
| Saccharomyces boulardii | ★★★★★ | Low |
| Phosphatidylcholine | ★★★★★ | Low |
| Evening Primrose Oil | ★★★★★ | Low |
| Chromium | ★★★★★ | Low |
| Borage | ★★★★★ | Low |
| Vitamin A | ★★★★★ | Low |
| Resveratrol | ★★★★★ | Low |
| N-Acetyl Cysteine (NAC) | ★★★★★ | Low |
| Jojoba | ★★★★★ | Low |
| Vitamin B9 (Folate) | ★★★★★ | Low |
Studies
Find individual evidence reviews for supplements sorted by DEX Score.
18 supplements for , and rated at least stars. All purchase bands. No minimum star filter.
ZincView supplement →
Consider purchase·★★★★★
How we scored this▸
- Taking zinc by mouth may help improve acne, but it’s not clear how well it works compared with common acne medicines.
- People with acne often have lower zinc levels in their blood and skin.
- Research shows that taking zinc sulfate or zinc gluconate 137 to 300 mg two or three times a day can modestly reduce acne, although results differ between studies.
- In one study, zinc sulfate 200 mg twice a day for 12 weeks improved acne about as well as lymecycline 300 mg daily.
- In another, zinc gluconate 30 mg daily for 3 months helped but wasn’t as effective as minocycline.
- Zinc creams alone don’t seem to work, but they can help when combined with erythromycin.
Browse 11 studies·1 meta-analysis
Open-labelAn Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris2021n=100
An open-label trial in 100 adolescents with mild-to-moderate acne found oral zinc sulphate and lymecycline both reduced GAGS scores over 12 weeks, with significantly greater acne-related quality-of-life gains in the zinc group.
- Effect
- Benefit
- Duration
- 12 weeks
- Population
- Children/adolescents
- Participants
- 100
MetaSerum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis2020
A meta-analysis found acne patients had lower serum zinc than controls and that zinc treatment significantly reduced inflammatory papule counts as monotherapy or adjunct therapy, without increased side effects.
- Effect
- Benefit
- Population
- Acne patients
RCTMulticenter randomized comparative double-blind controlled clinical trial of the safety and efficacy of zinc gluconate versus minocycline hydrochloride in the treatment of inflammatory acne vulgaris2001n=332
In 332 patients with inflammatory acne, 30 mg/day elemental zinc gluconate for 3 months achieved a 31.2% clinical success rate versus 63.4% with minocycline, indicating minocycline was about 17% more effective.
- Effect
- Benefit
- Duration
- 3 months
- Dose
- 30 mg/day
- Population
- Acne patients
- Participants
- 332
RCTA double-blind controlled evaluation of the sebosuppressive activity of topical erythromycin-zinc complex1995n=14
In 14 volunteers, 4% erythromycin plus 1.2% zinc applied to half the forehead for 3 months significantly reduced sebum excretion rate and lipid spot area versus erythromycin alone.
- Effect
- Benefit
- Duration
- 3 months
- Dose
- 1.2% zinc (topical, twice daily)
- Population
- Adults
- Participants
- 14
Controlled trialTopical erythromycin and zinc therapy for acne1990n=39
In 73 women with acne, 4% erythromycin plus 1.2% zinc acetate for 12 weeks significantly improved global severity and lesion counts versus vehicle; benefits persisted through 1 year in 39 completers.
- Effect
- Benefit
- Duration
- 12 weeks
- Dose
- 1.2% zinc acetate (topical)
- Population
- Patients
- Participants
- 39
RCTA 4% erythromycin and zinc combination (Zineryt) versus 2% erythromycin (Eryderm) in acne vulgaris: a randomized, double-blind comparative study1989n=122
In 122 acne patients, Zineryt (4% erythromycin plus zinc) reduced lesion counts and severity grades more effectively over 12 weeks than 2% erythromycin alone.
- Effect
- Benefit
- Duration
- 12 weeks
- Population
- Acne patients
- Participants
- 122
Controlled trialTopical zinc therapy for acne vulgaris1985n=30
A 12-week double-blind study in 30 mild-to-moderate acne patients found topical 2% zinc sulfate did not reduce lesion counts versus placebo and caused significantly greater skin irritation.
- Effect
- No Benefit
- Duration
- 12 weeks
- Dose
- 2% zinc sulfate (topical)
- Population
- Patients
- Participants
- 30
RCTTopical erythromycin with zinc in acne. A double-blind controlled study1980n=49
In 141 acne patients, topical 4% erythromycin with 1.2% zinc liquid or gel twice daily matched oral tetracycline and outperformed placebo on severity grade and papule counts over 10 weeks.
- Effect
- Benefit
- Duration
- 10 weeks
- Dose
- 250 mg 2×/day
- Population
- Acne patients
- Participants
- 49
Controlled trialA double-blind trial of a zinc sulphate/citrate complex and tetracycline in the treatment of acne vulgaris1979n=48
In 48 acne patients over 3 months, oral tetracycline significantly reduced overall grade and most lesion types, whereas a zinc sulphate/citrate complex only significantly reduced pustules at month 3.
- Effect
- Benefit
- Duration
- 3 months
- Population
- Patients
- Participants
- 48
RCTZinc sulfate in acne vulgaris1978n=40
In 40 acne patients treated 12 weeks, oral zinc sulfate showed a modest benefit on pustules only; 50% of the zinc group had nausea, vomiting, or diarrhea and 21% withdrew.
- Effect
- Benefit
- Duration
- 12 weeks
- Population
- Patients
- Participants
- 40
RCTA double-blind study of the effect of zinc and oxytetracycline in acne vulgaris1977n=37
In 37 patients with moderate-to-severe acne, oral zinc and oxytetracycline over 12 weeks produced similar roughly 70% reductions in acne scores with no reported side effects in either group.
- Effect
- Benefit
- Duration
- 12 weeks
- Population
- Patients
- Participants
- 37
AloeView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- A study showed that putting on aloe gel twice a day, together with acne cream and daily washing, helped reduce pimples more than using the cream and washing alone.
Browse 1 study
RCTEffect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial2014n=60
An 8-week RCT in 60 acne patients found tretinoin plus Aloe vera gel reduced inflammatory and non-inflammatory lesions with less irritation than tretinoin plus vehicle alone.
- Effect
- Benefit
- Duration
- 8 weeks
- Participants
- 60
Milk ThistleView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- Research on milk thistle for acne shows mixed results. A small study found that taking 140 mg of silymarin daily for 2 months did not improve acne and was less effective than doxycycline, a common medication for acne. Using silymarin along with doxycycline did not seem to provide extra benefit.
- Some topical products containing milk thistle have shown moderate improvements in acne after a few months, but these studies are small and don’t compare the products to other treatments. Another Korean study reported that a cream with silymarin and other ingredients improved acne over 4–12 weeks, but more research is needed to confirm these effects.
Browse 6 studies
A Silymarin Antioxidant Serum Improves Facial Acne Alone and as Part of a Treatment Regimen2024n=56
A 12-week study of 56 blemish-prone patients found a silymarin antioxidant serum reduced inflammatory acne lesions by 45% and noninflammatory lesions by 43%.
- Effect
- Benefit
- Duration
- 12 weeks
- Participants
- 56
ObservationalTolerability and effectiveness of a dermocosmetic product containing Silybum marianum fruit extract in adolescents and young adults with acne-prone skin: An international, phase IV, longitudinal study2023n=4,230
An observational study of 4,230 adolescents and young adults with acne-prone skin found a Silybum marianum extract product was rated effective or highly effective in about 80% of patients after 8–12 weeks.
- Effect
- Benefit
- Population
- Young adults
- Participants
- 4,230
- Ages
- 12–25
Clinical trialTopical Silymarin Cream as a Novel Therapy Versus Salicylic Acid Peels in Acne Vulgaris: A Split-Face Clinical Trial2023n=30
A split-face trial of 30 mild-to-moderate acne patients found 1.4% silymarin cream twice daily for 3 months reduced Global Acne Grading System scores comparably to salicylic acid 30% peels.
- Effect
- Benefit
- Duration
- 3 months
- Population
- Adults with acne vulgaris
- Participants
- 30
Open-labelEfficacy and safety of silymarin containing antioxidant serum as an adjuvant treatment of mild-to-moderate acne vulgaris: A prospective, open-label pilot study2022
An open-label pilot study of 22 acne patients found 0.5% silymarin antioxidant serum twice daily for 4 weeks significantly reduced acne severity scores and melanin pigmentation.
- Effect
- Benefit
- Duration
- 4 weeks
- Population
- Adults with acne
RCTEfficacy and safety of oral silymarin in comparison with oral doxycycline and their combination therapy in the treatment of acne vulgaris2019n=60
An RCT of 60 acne vulgaris patients found oral silymarin was not significantly different from doxycycline on Global Acne Grading System scores but was less effective on the Acne Severity Index.
- Effect
- Benefit
- Population
- Adults with acne vulgaris
- Participants
- 60
Effects of Oral Antioxidants on Lesion Counts Associated with Oxidative Stress and Inflammation in Patients with Papulopustular Acne2012
A study of patients with papulopustular acne found oral antioxidant supplementation reduced acne lesion counts and markers of oxidative stress and inflammation.
Vitamin DView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- It is not clear whether taking vitamin D by mouth helps improve acne.
- One small study in people with low vitamin D and acne showed that taking 1000 IU of vitamin D daily for two months reduced red, inflamed pimples by about 35%, while those taking placebo had only a 6% reduction.
- Another study showed that a special form of vitamin D (alfacalcidol) taken daily for three months also helped reduce acne a little.
- People with acne often have lower vitamin D levels and are more likely to be vitamin D deficient than those without acne.
Browse 4 studies·1 meta-analysis
RCTRole of vitamin D supplement adjunct to topical benzoyl peroxide in acne: a randomized double-blinded controlled study2024n=44
An RCT in 44 acne patients on benzoyl peroxide found weekly 40,000 IU vitamin D2 prevented inflammatory lesion relapse at 4-week follow-up.
- Effect
- Benefit
- Duration
- 12 weeks
- Dose
- 40000 IU/day
- Population
- RA patients
- Participants
- 44
- Ages
- 20–45
MetaAssociation between Vitamin D Level and Acne, and Correlation with Disease Severity: A Meta-Analysis2022n=2,443
A meta-analysis of 13 studies (2,443 participants) found acne patients had lower 25(OH)D levels and higher vitamin D deficiency prevalence (OR 2.97).
- Population
- Acne patients
- Participants
- 2,443
RCTThe impact of active vitamin D administration on the clinical outcomes of acne vulgaris2021n=100
An RCT in 100 acne patients found 0.25 µg/day alfacalcidol for 3 months improved acne severity versus placebo in those with low baseline vitamin D.
- Effect
- Benefit
- Duration
- 3 months
- Dose
- 0.25 mcg/day
- Population
- Patients With Acne And 100 Healthy Controls
- Participants
- 100
RCTComparison of Vitamin D Levels in Patients with and without Acne: A Case-Control Study Combined with a Randomized Controlled Trial2016n=80
A case-control plus RCT in 80 acne patients found vitamin D deficiency was common (49%) and 1,000 IU/day for 2 months improved inflammatory lesions.
- Effect
- Benefit
- Duration
- 2 months
- Dose
- 1000 IU/day
- Population
- Children
- Participants
- 80
Green TeaView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- Applying green tea extract directly to the skin can help reduce both red, inflamed pimples and non-inflamed acne spots.
- Using creams or lotions with green tea ingredients like EGCG twice daily for 8 weeks has been shown to improve acne a little bit.
- Drinking green tea or taking green tea supplements by mouth has not shown strong evidence for improving acne so far.
- More research is needed to know if drinking green tea helps.
Browse 2 studies·1 meta-analysis
MetaThe effects of green tea on acne vulgaris: A systematic review and meta-analysis of randomized clinical trials2021n=247
A meta-analysis of 5 RCTs (247 patients) found green tea extract significantly reduced inflammatory acne lesion counts versus control.
- Effect
- Benefit
- Participants
- 247
RCTEpigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes2013
In human sebocyte and patient studies, epigallocatechin-3-gallate reduced sebum production and acne inflammation by modulating AMPK-SREBP-1 and NF-κB pathways.
- Effect
- Benefit
- Population
- Adults
Vitamin B3 (Niacin)View supplement →
Reconsider purchase·★★★★★
How we scored this▸
- Evidence is insufficient for this condition.
Browse 3 studies
RCTTopical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris2013n=40
A randomized trial of 40 patients with moderate inflammatory facial acne vulgaris found that in this randomized, double-blind clinical trial, patients with moderate inflammatory facial acne vulgaris were randomly allocated to receive either topical 4% nicotinamide (n = 40) or 1% clindamycin gels (n = 40) twice daily.
- Effect
- Benefit
- Population
- Patients With Moderate Inflammatory Facial Acne Vulgaris
- Participants
- 40
1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin2003
A study found that mNA+ can be used to treat wide variety of diseases and disorders and the use of this compound provides certain advantages over the use of nicotinamide.
RCTTopical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris1995n=38
A randomized trial of 38 found that after 8 weeks, both treatments produced comparable (P = 0.19) beneficial results in the Physician's Global Evaluation of Inflammatory Acne; 82% of the patients treated with nicotinamide gel and 68% treated with clindamycin gel were improved.
- Effect
- Benefit
- Duration
- 8 weeks
- Population
- Acne patients
- Participants
- 38
BorageView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- It is unclear if taking borage seed oil helps improve acne.
- One small study found that taking 2 grams of borage oil daily for 10 weeks reduced acne spots by about one-third and less severe acne lesions by about one-sixth.
- These results were better than no treatment and similar to taking other omega-3 fatty acids.
Browse 1 study
RCTEffect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial2014n=45
In 45 adults with mild-to-moderate acne, 12 weeks of combined omega-3 (2 g/day) and borage oil (400 mg GLA/day) significantly reduced inflammatory and non-inflammatory lesion counts versus control.
- Effect
- Benefit
- Duration
- 10 weeks
- Dose
- 2000 mg/day
- Population
- Adults
- Participants
- 45
ChromiumView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- A clinical trial found that a supplement containing chromium alongside other vitamins, minerals, and plant extracts helped reduce acne spots and improve overall skin condition in people with mild to moderate acne over about 3 months.
- People taking the supplement had fewer red and non-red acne spots and felt better about their skin.
- The supplement was safe and well tolerated.
- Other research shows that chromium supplements may help reduce acne and inflammation in women with PCOS by improving blood sugar control and lowering body-wide inflammation.
- More studies are needed to confirm these benefits.
Browse 1 study
RCTA 12-week, Randomized, Double-blind, Placebo-controlled Study of the Safety and Efficacy of a Nutraceutical Supplement for Mild to Moderate Non-cystic Acne in Young Adults2024n=26
In a 12-week trial of 40 adults with mild-to-moderate non-cystic acne, a vitamin-mineral-botanical supplement reduced inflammatory and non-inflammatory lesions versus placebo.
- Duration
- 84 days
- Population
- Young adults
- Participants
- 26
Evening Primrose OilView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- No summary is available.
Browse 1 study
RCTEffect of Evening Primrose Oil Supplementation on Biochemical Parameters and Nutrition of Patients Treated with Isotretinoin for Acne Vulgaris: A Randomized Double-Blind Trial2022n=25
A 9-month study of 50 young adults (average age 22.5 years old) with moderate to severe acne found that isotretinoin (10-40 mg/day) + evening primrose oil (4 x 510 mg/day) improved total cholesterol (mean -6% vs. +21%), LDL (-33% vs. +37%), HDL (+12% vs. -2%), triglycerides (+3% vs. +24%), AST (-4% vs. +17%) and ALT (-4% vs. +14%) when compared to isotetinoin alone. [10713]
- Effect
- Benefit
- Duration
- 9 months
- Dose
- 510 mg/day
- Population
- Young adults
- Participants
- 25
- Avg age
- ~22
PhosphatidylcholineView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- Using a cream that has both niacinamide and phosphatidylcholine with linoleic acid may help improve skin moisture and reduce acne and redness better than some antibiotic creams or simple moisturizers.
- This was shown in a study on people aged 15 and older with moderate acne.
- It is not clear how much phosphatidylcholine alone contributes to these benefits.
Browse 1 study
RCTTopical clindamycin 1% vs. linoleic acid-rich phosphatidylcholine and nicotinamide 4% in the treatment of acne: a multicentre-randomized trial2011
A 12-week trial found 4% nicotinamide-phospholipid emulsion slightly outperformed 1% topical clindamycin for acne on global clinical improvement and compliance.
- Effect
- Benefit
- Duration
- 12 weeks
Saccharomyces boulardiiView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- Early research shows that taking Saccharomyces boulardii strain CBS 5926 (Perenterol) daily for 5 months helped 80% of people feel better, compared with only 26% who took a placebo.
Browse 1 study
RCT[Treatment of acne with a yeast preparation]1989n=139
In 139 acne patients, Perenterol yeast was effective or very good in 74.3% versus 21.7% on placebo over up to 5 months.
- Effect
- Benefit
- Population
- Patients with various forms of acne
- Participants
- 139
SeleniumView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- Selenium has insufficient evidence for Acne.
Browse 2 studies
RCTA 12-week, Randomized, Double-blind, Placebo-controlled Study of the Safety and Efficacy of a Nutraceutical Supplement for Mild to Moderate Non-cystic Acne in Young Adults2024n=26
In a 12-week trial of 40 adults with mild-to-moderate non-cystic acne, a vitamin-mineral-botanical supplement reduced inflammatory and non-inflammatory lesions versus placebo.
- Effect
- Benefit
- Duration
- 84 days
- Population
- Young adults
- Participants
- 26
Effects of Oral Antioxidants on Lesion Counts Associated with Oxidative Stress and Inflammation in Patients with Papulopustular Acne2012
A study evaluated oral antioxidants including selenium on papulopustular acne lesion counts; published abstract details on dose, duration, and outcomes were not available.
- Population
- Patients with Papulopustular Acne
Vitamin B2 (Riboflavin)View supplement →
Reconsider purchase·★★★★★
How we scored this▸
- A small study in adults with mild to moderate acne found that using a riboflavin gel on the face before light therapy helped reduce acne spots as well as another common treatment gel.
- However, taking riboflavin as a pill for acne has not been proven to be helpful.
Browse 1 study
RCTTopical riboflavin versus 5-aminolevulinic acid photodynamic therapy for the treatment of mild to moderate acne: A split-face randomized study https://pubmed.ncbi.nlm.nih.gov/39709022/2025n=30
A randomized trial of 30 found that both ALA and riboflavin-PDT significantly reduced non-inflammatory and inflammatory lesions at weeks 4, 6, and 10 compared to baseline (P all <0.001).
- Effect
- Benefit
- Participants
- 30
JojobaView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- There is very little evidence on whether jojoba oil helps acne.
- In one small study, people used a clay facial mask with jojoba oil for 15 minutes, two to three times a week, over 6 weeks.
- They showed fewer pimples, blackheads, and whiteheads, but the study was not well designed because there was no comparison group, so it is unclear if jojoba oil truly helps.
Browse 1 study
Clinical trialClay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study2012n=194
In 194 adults with mild acne, clay-jojoba oil facial masks 2–3 times weekly for 6 weeks reduced total lesion count by 54% (pustules −49%, papules −57%) with improved quality of life.
- Effect
- Benefit
- Duration
- 6 weeks
- Population
- Adults
- Participants
- 194
- Avg age
- 32.3±0.7
N-Acetyl Cysteine (NAC)View supplement →
Reconsider purchase·★★★★★
How we scored this▸
- There isn’t enough research to know if N-acetylcysteine helps with acne.
- One small study looked at oral antioxidants and saw some improvement in inflammatory acne lesions, but NAC itself hasn’t been well studied for this use.
Browse 1 study
Effects of Oral Antioxidants on Lesion Counts Associated with Oxidative Stress and Inflammation in Patients with Papulopustular Acne2012
A clinical study found oral antioxidants including NAC reduced acne lesion counts associated with oxidative stress, though evidence remains limited.
ResveratrolView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- It is not clear if resveratrol gel helps acne.
- In an early study, using a gel with a small amount of resveratrol on the face for two months reduced acne severity by about half, while a placebo gel only reduced acne a little.
Browse 1 study
Controlled trialResveratrol-containing gel for the treatment of acne vulgaris: a single-blind, vehicle-controlled, pilot study2011n=20
In 20 adults with acne over 60 days, a resveratrol-containing gel reduced inflammatory lesions versus vehicle control in this single-blind pilot study.
- Effect
- Benefit
- Duration
- 60 days
- Population
- Adults
- Participants
- 20
Vitamin AView supplement →
Reconsider purchase·★★★★★
How we scored this▸
- Some prescription vitamin A medications are approved to treat acne, but it’s not clear if over-the-counter vitamin A skin products (like retinol) really help.
- A small study found that using a retinol product with salicylic acid at night, along with benzoyl peroxide in the morning, improved acne a little over 12 weeks.
- However, because there was no comparison group, it’s hard to say for sure how effective these non-prescription products really are.
Browse 1 study
A Topical Combination Regimen of Benzoyl Peroxide and Retinol Moisturizer for Mild to Moderate Acne2022n=33
A study of 33 adults with mild-to-moderate acne found morning 2.5% benzoyl peroxide plus evening topical retinol for 12 weeks significantly reduced total acne lesions and improved skin appearance.
- Effect
- Benefit
- Duration
- 12 weeks
- Population
- Adults
- Participants
- 33
Vitamin B9 (Folate)View supplement →
Do not purchase·★★★★★
How we scored this▸
- Folic acid has only been tested together with other ingredients, so its effect by itself is not clear.
- Early research in adults and children with inflammatory acne found that taking a product called NicAzel, which contains folic acid and several other vitamins and minerals, for 8 weeks helped reduce acne spots and improve skin appearance in most people.
Browse 1 study
Open-labelInflammatory acne management with a novel prescription dietary supplement2012n=235
A study of 235 women found that at week 8, 88% of the patients experienced a visible reduction in inflammatory lesions, and 81% of the patients rated their appearance as much or moderately better compared with baseline.
- Duration
- 8 weeks
- Population
- Women
- Participants
- 235
Evidence visualised
Same ratings as above, aggregated so you can see coverage and imbalance.
| Supplement | DEX | Studies | Meta-analyses | Share |
|---|---|---|---|---|
| Zinc | ★★★★★68% | 11 | 1 | 28% |
| Milk Thistle | ★★★★★52% | 6 | 0 | 15% |
| Vitamin D | ★★★★★52% | 4 | 1 | 10% |
| Vitamin B3 (Niacin) | ★★★★★48% | 3 | 0 | 8% |
| Green Tea | ★★★★★48% | 2 | 1 | 5% |
| Selenium | ★★★★★44% | 2 | 0 | 5% |
| Aloe | ★★★★★56% | 1 | 0 | 3% |
| Borage | ★★★★★44% | 1 | 0 | 3% |
| Chromium | ★★★★★44% | 1 | 0 | 3% |
| Evening Primrose Oil | ★★★★★44% | 1 | 0 | 3% |
| Jojoba | ★★★★★40% | 1 | 0 | 3% |
| N-Acetyl Cysteine (NAC) | ★★★★★40% | 1 | 0 | 3% |
| Phosphatidylcholine | ★★★★★44% | 1 | 0 | 3% |
| Resveratrol | ★★★★★40% | 1 | 0 | 3% |
| Saccharomyces boulardii | ★★★★★44% | 1 | 0 | 3% |
| Vitamin A | ★★★★★40% | 1 | 0 | 3% |
| Vitamin B2 (Riboflavin) | ★★★★★44% | 1 | 0 | 3% |
| Vitamin B9 (Folate) | ★★★★★36% | 1 | 0 | 3% |