Abdominal pain

Overview

SupplementDEX currently indexes Probiotics for abdominal pain. See the heatmap and evidence reviews below for the full rating.

Effect graph

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Probiotics	★★★★★	Medium

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Studies

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1 supplement for rated at least stars. All purchase bands. No minimum star filter.

ProbioticsView supplement →

Consider purchase★★★★★

How we scored this

Effect SizeMediumEvidenceHighTrustVery High

Evidence Review

Probiotics are possibly effective for Abdominal pain.

Browse 5 studies1 meta-analysis

RCTThe effect of probiotic supplementation on episiotomy wound healing among primiparous women: a triple-blind randomized clinical trial2023n=74

In 74 primiparous women, Lactobacillus casei 431 for 14 days after episiotomy improved wound healing scores versus placebo at 5 and 15 days postpartum.

Effect: Benefit
Duration: 14 days
Population: Women
Participants: 74

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MetaUse of probiotics in the treatment of functional abdominal pain in children-systematic review and meta-analysis2021n=380

A meta-analysis of 9 pediatric RCTs found Lactobacillus reuteri DSM 17938 reduced functional abdominal pain intensity (MD −1.24) and increased pain-free days versus placebo.

Effect: Benefit
Population: Children/adolescents
Participants: 380
Ages: 4–18

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RCTLactobacillus reuteri DSM 17938 is effective in the treatment of functional abdominal pain in children: Results of the double-blind randomized study2020n=46

In 46 children with functional abdominal pain, L. reuteri DSM 17938 10^8 CFU/day for 12 weeks reduced pain severity and increased pain-free days versus placebo in this RCT.

Effect: Benefit
Duration: 12 weeks
Dose: 10^8 CFU/day L. reuteri
Population: Children/adolescents
Participants: 46
Ages: 4–18

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RCTLactobacillus reuteri DSM 17938 and a placebo both significantly reduced symptoms in children with functional abdominal pain2017n=27

In 54 children with functional abdominal pain, both L. reuteri and placebo significantly reduced pain frequency and intensity at 4 and 8 weeks; L. reuteri also cut rescue medication use.

Effect: No Benefit
Population: Adults
Participants: 27
Avg age: ~9

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RCTLactobacillus acidophilus NCFM affects colonic mucosal opioid receptor expression in patients with functional abdominal pain - a randomised clinical study2014n=20

In 20 adults with functional abdominal pain, Lactobacillus acidophilus NCFM alone increased colonic mu-opioid receptor expression; symptom improvements trended but were underpowered.

Effect: Benefit
Duration: 21 days
Dose: 2×10^10 CFU/day L. acidophilus
Population: Women
Participants: 20
Ages: 18–70

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Evidence visualised

Same ratings as above, aggregated so you can see coverage and imbalance.

Purchase-guidance distribution

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Effect-size distribution

How large the reported benefits tend to be

Study distribution across 1 supplements for abdominal pain (5 studies total).
Supplement	DEX	Studies	Meta-analyses	Share
Probiotics	★★★★★72%	5	1	100%

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Overview

Effect graph

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Studies

Evidence visualised

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