Age-related Macular Degeneration (AMD)
Supplements studied for age-related macular degeneration (AMD).
Overview
Eight supplements are indexed for age-related macular degeneration (AMD) across 62 studies. Lutein and Multivitamin carry the strongest ratings (DEX Score 68, medium across dimensions).
Lutein may improve glare recovery, dim-light vision, and macular pigment, but does not appear to stop AMD progression or prevent severe vision loss. A multivitamin/mineral combination (vitamin C, E, beta-carotene, and sometimes zinc) may reduce advanced-AMD vision loss and disease progression in high-risk people over years of use.
Fish Oil (DEX Score 40; very low effect size, high evidence, medium trust) and Vitamin E alone (DEX Score 40) do not prevent or slow AMD in large trials, though vitamin E as part of the antioxidant-zinc combination may contribute to benefit. Lycopene evidence is inconsistent. See the heatmap and evidence reviews below for all eight supplements.
Effect graph
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Relevant supplements heatmap
Relevant supplements sorted by DEX Score.
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SupplementDEX Database
9 supplements for and rated at least stars. All purchase bands. No minimum star filter.
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Visual summaries of supplement evidence ranked by condition.
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