Sickle cell disease
Supplements studied for sickle cell disease.
Overview
Zinc (7 studies) has the most evidence for sickle cell disease, with trials suggesting it may reduce pain crises, infections, hospital stays, and transfusion needs—especially in zinc-deficient patients. A prescription glutamine product (Endari) is approved to reduce serious complications, though no SupplementDEX trials are listed.
Vitamin D (1 study) may reduce pain days and improve activity in children with low levels. Riboflavin and Niacin (each 1 study) showed no meaningful clinical benefit. See the heatmap and evidence reviews below.
Effect graph
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Relevant supplements heatmap
Relevant supplements sorted by DEX Score.
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SupplementDEX Database
4 supplements for , and rated at least stars. All purchase bands. No minimum star filter.
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Evidence visualised
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Visual summaries of supplement evidence ranked by condition.
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