SupplementDEX

Beta-Glucan

Beta-glucans are fiber compounds studied for cholesterol, glucose, and immune outcomes depending on source and dose.

Overview

What are beta-glucans?

Beta-glucans are a type of soluble fiber that is found in oats and barley. Beta-glucans are the fibers found in the cell walls of cereals, fungi, and bacteria, composed of glucose molecules linked by β-glycosidic bonds. Their structure varies by source, influencing their biological effects, with cereal beta-glucans supporting metabolic health and fungal beta-glucans known for immune modulation. Greater intake of beta-glucans may reduce the risk of heart disease and reduce cholesterol absorption from foods.

Dosage

A typical dose of 3 grams per day beta-glucans (barley and oats) has been used for lowering cholesterol, blood glucose and insulin.

A typical dose of yeast-derived beta-glucans is 250 mg per day.

Effect graph

Effect heatmap

SupplementDEX Database

16 conditions for and rated at least stars. All purchase bands. No minimum star filter.

Database Snapshot

Studies per condition
Beta-Glucan evidence base by condition

Most beta-glucan research is concentrated in a handful of conditions.

  • High cholesterol accounts for 19 of 67 studies (28%).
  • Coronary heart disease accounts for 15 of 67 studies (22%).
  • Diabetes accounts for 9 of 67 studies (13%).
  • Sparse coverage remains for Upper respiratory tract infection, Atopic dermatitis (eczema), Canker sores.
Studies per year
Beta-Glucan publications over time

Dietary Sources

Top dietary sources

Food sources

High amounts of beta-glucans are found in common foods. Foods containing beta-glucans

Sources include Barley, Durum Wheat, Maize, Mushrooms, Oats, Rice, Rye, Seaweed, Sorghum, and Wheat.

Safety

Oral beta-glucans are generally safe and well tolerated when consumed through foods.

Frequently Asked Questions

References

Sources64 references

SupplementDEX uses only high-quality sources to determine supplement effectiveness.

  1. 1.SupplementDEX Database: Coronary heart diseaseDietary fiber, weight gain, and cardiovascular disease risk factors in young adults1999

    In 2,909 CARDIA participants followed 10 years, higher dietary fiber intake was linearly associated with lower body weight, waist-to-hip ratio, and fasting insulin in both black and white young adults.

  2. 2.SupplementDEX Database: Coronary heart diseaseCholesterol-lowering effects of dietary fiber: a meta-analysis1999

    A meta-analysis of 67 controlled trials found 2–10 g/day soluble fiber (pectin, oat bran, guar, psyllium) significantly lowered total cholesterol (~0.045 mmol/L per g) and LDL cholesterol (~0.057 mmol/L per g).

  3. 4.SupplementDEX Database: Coronary heart diseaseFiber, lipids, and coronary heart disease. A statement for healthcare professionals from the Nutrition Committee, American Heart Association1997

    An American Heart Association scientific statement summarized evidence that dietary fiber, particularly soluble fiber, improves lipid profiles and may lower coronary heart disease risk.

  4. 5.SupplementDEX Database: Coronary heart diseaseIntake of dietary fiber and risk of coronary heart disease in a cohort of Finnish men. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study1996

    In 21,930 Finnish smoking men followed 6.1 years, highest total fiber intake (median 34.8 g/day) was associated with 31% lower coronary death risk versus the lowest quintile (16.1 g/day), independent of other risk factors.

  5. 6.SupplementDEX Database: Coronary heart diseaseVegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men1996

    In 43,757 US male health professionals followed 6 years, men in the highest fiber quintile (28.9 g/day) had 41% lower fatal CHD risk than those in the lowest quartile (12.4 g/day).

  6. 7.SupplementDEX Database: Coronary heart diseaseGreater dietary oat and buckwheat intakes prevent and treat both hypertension and hypercholesterolemia in an ethnic minority of China1995

    In 850 Yi adults in China, 100 g/day oats intake was associated with lower BMI, blood pressure, and HDL cholesterol; 100 g/day buckwheat with lower total and LDL cholesterol.

  7. 8.SupplementDEX Database: Coronary heart diseaseOat beta-glucan reduces blood cholesterol concentration in hypercholesterolemic subjects1994

    In 19 hypercholesterolemic adults, 2.9 g/day purified oat beta-glucan for 4 weeks reduced fasting total cholesterol and LDL cholesterol by 9% each versus baseline; levels returned after stopping supplementation.

  8. 9.SupplementDEX Database: Coronary heart diseaseOat products and lipid lowering. A meta-analysis1992

    A meta-analysis of 10 oat trials found blood total cholesterol fell by 0.13 mmol/L (~5.9 mg/dL) with oat products; larger reductions occurred when baseline cholesterol was ≥5.9 mmol/L and soluble fiber dose was ≥3 g/day.

  9. 10.SupplementDEX Database: Coronary heart diseaseThe hypocholesterolemic effects of beta-glucan in oatmeal and oat bran. A dose-controlled study1991

    In 156 hypercholesterolemic adults, 6 weeks of 56–84 g/day oatmeal or oat bran reduced LDL cholesterol by 10–16% versus farina control; 56 g oat bran lowered LDL more than 56 g oatmeal, supporting a beta-glucan dose effect.

  10. 11.SupplementDEX Database: Coronary heart diseaseLipid responses of hypercholesterolemic men to oat-bran and wheat-bran intake1991

    In 20 hypercholesterolemic men on a metabolic ward, 21 days of oat bran lowered total cholesterol by 12.8% and LDL by 12.1%, while matched wheat bran had no significant lipid effect.

  11. 12.SupplementDEX Database: Coronary heart diseaseDietary fiber and reduced ischemic heart disease mortality rates in men and women: a 12-year prospective study1987

    In 859 southern Californians aged 50–79 followed 12 years, dietary fiber ≥16 g/day was associated with 67% lower ischemic heart disease mortality in men and 63% lower in women versus lower intake.

  12. 13.SupplementDEX Database: Coronary heart diseaseSerum lipid response to oat product intake with a fat-modified diet1986

    In 208 adults on a fat-modified diet, adding 60 g/day oat bran or oatmeal for 6 weeks further lowered mean serum cholesterol by 5.6–6.5 mg/dL beyond diet alone (p<0.05).

  13. 14.SupplementDEX Database: Coronary heart diseaseDiet, prevalence and 10-year mortality from coronary heart disease in 871 middle-aged men. The Zutphen Study1984

    In 871 middle-aged Dutch men followed 10 years, higher vegetable protein, polysaccharides, and dietary fiber were inversely related to CHD mortality, though associations attenuated after adjusting for energy intake per kg body weight.

  14. 15.SupplementDEX Database: Coronary heart diseaseDiet and heart: a postscript1977

    In 337 middle-aged London men followed to 1976, high cereal fiber intake was independently associated with lower coronary heart disease rates; polyunsaturated-to-saturated fat ratio showed a non-significant protective trend.

  15. 3.FDA: "soluble fiber from whole oats" and claims on foods relating to the consumption of soluble fiber from whole oats to reduced risk of heart disease are justified. See external sourceExternal source
    No source link
  1. 16.SupplementDEX Database: DiabetesThe effect of oat β-glucan on postprandial blood glucose and insulin responses: a systematic review and meta-analysis2021

    A meta-analysis of 103 trial comparisons (538 participants) found oat beta-glucan reduced postprandial glucose iAUC by 23% and insulin iAUC by 22%, with larger effects at higher dose and molecular weight >300 kg/mol.

  2. 17.SupplementDEX Database: DiabetesEffect of High β-glucan Barley on Postprandial Blood Glucose and Insulin Levels in Type 2 Diabetic Patients2020

    In 10 type 2 diabetic patients, a meal with 50% high beta-glucan barley mixed with white rice significantly lowered postprandial glucose and C-peptide iAUC versus white rice alone.

  3. 18.SupplementDEX Database: DiabetesThe effect of beta-glucan supplementation on glycemic control and variability in adolescents with type 1 diabetes mellitus2020

    In 30 adolescents with type 1 diabetes, 6 g/day oat beta-glucan for 1 week lowered mean, premeal/postmeal, and peak glucose and reduced glycemic variability (SD, CV, LBGI, CONGA) versus lower doses.

  4. 19.SupplementDEX Database: DiabetesA Multifunctional Bread Rich in Beta Glucans and Low in Starch Improves Metabolic Control in Type 2 Diabetes: A Controlled Trial2017

    In matched type 2 diabetic patients, ~6 months of beta-glucan-rich, low-starch functional bread reduced HbA1c by ~0.5–0.6% versus regular white bread and lowered postprandial and mean glucose.

  5. 20.SupplementDEX Database: DiabetesEffect of Oral Pre-Meal Administration of Betaglucans on Glycaemic Control and Variability in Subjects with Type 1 Diabetes2017

    In 14 adults with type 1 diabetes, 4.59 g/day oat beta-glucan before meals for 2 weeks did not improve glycemic control or variability versus placebo in this pilot crossover study.

  6. 21.SupplementDEX Database: DiabetesEffect of Oat β-Glucan Intake on Glycaemic Control and Insulin Sensitivity of Diabetic Patients: A Meta-Analysis of Randomized Controlled Trials2016

    A meta-analysis of 4 RCTs (350 type 2 diabetic patients) found 2.5–3.5 g/day oat beta-glucan for 3–8 weeks lowered fasting glucose by 0.52 mmol/L and HbA1c by 0.21% versus control.

  7. 22.SupplementDEX Database: DiabetesA controlled study of consumption of beta-glucan-enriched soups for 2 months by type 2 diabetic free-living subjects2010

    In 53 type 2 diabetic adults, 3.5 g/day beta-glucan in soup for 8 weeks significantly lowered triglycerides versus control but did not change total cholesterol, LDL, HDL, HbA1c, or fasting glucose.

  8. 23.SupplementDEX Database: DiabetesThe consumption of bread enriched with betaglucan reduces LDL-cholesterol and improves insulin resistance in patients with type 2 diabetes2009

    In 46 type 2 diabetic patients, 3 weeks of beta-glucan-enriched bread (3 g/day) lowered LDL cholesterol by 0.66 mmol/L (16%), total cholesterol by 0.80 mmol/L, fasting insulin, and HOMA-IR versus control bread.

  9. 24.SupplementDEX Database: DiabetesInfluence of a beta-glucan-enriched bedtime snack on nocturnal blood glucose levels in diabetic children2001

    In 38 children with diabetes, a beta-glucan-enriched bedtime snack flattened the pre-midnight glucose curve but did not reduce the 27% prevalence of hypoglycemia at 2 AM versus a conventional snack.

  1. 25.SupplementDEX Database: High cholesterolEffects of Oat Beta-Glucan Intake on Lipid Profiles in Hypercholesterolemic Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials2022

    A meta-analysis of 13 RCTs (927 hypercholesterolemic adults) found oat beta-glucan significantly lowered total cholesterol by 0.24 mmol/L and LDL by 0.27 mmol/L, without significant effects on triglycerides or HDL.

  2. 26.SupplementDEX Database: High cholesterolThe separate effects of whole oats and isolated beta-glucan on lipid profile: A systematic review and meta-analysis of randomized controlled trials2022

    A meta-analysis of 28 RCTs (1,494 subjects) found both whole oats and isolated beta-glucan significantly improved total cholesterol and LDL versus control in hyperlipidemic adults.

  3. 27.SupplementDEX Database: High cholesterolThe effect of oat β-glucan on LDL-cholesterol, non-HDL-cholesterol and apoB for CVD risk reduction: a systematic review and meta-analysis of randomised-controlled trials2016

    A meta-analysis of 58 RCTs found a median dose of 3.5 g/day oat beta-glucan lowered LDL by 0.19 mmol/L, non-HDL cholesterol by 0.20 mmol/L, and apoB by 0.03 g/L versus control.

  4. 28.SupplementDEX Database: High cholesterolCholesterol-lowering effects of oat β-glucan: a meta-analysis of randomized controlled trials2014

    A meta-analysis of 28 RCTs found ≥3 g/day oat beta-glucan reduced LDL by 0.25 mmol/L and total cholesterol by 0.30 mmol/L; effects were greater with higher baseline LDL and in people with diabetes.

  5. 29.SupplementDEX Database: High cholesterolEffect of 6 weeks' consumption of β-glucan-rich oat products on cholesterol levels in mildly hypercholesterolaemic overweight adults2012

    In 87 mildly hypercholesterolemic adults, 6 weeks of 1.5 or 3.0 g/day oat beta-glucan from flakes lowered total and LDL cholesterol similarly; all groups including control showed significant cholesterol reductions.

  6. 30.SupplementDEX Database: High cholesterolBeta-glucan- or rice bran-enriched foods: a comparative crossover clinical trial on lipidic pattern in mildly hypercholesterolemic men2011

    In 24 mildly hypercholesterolemic men, a 4-week beta-glucan-enriched diet lowered LDL by 0.21 mmol/L more than a rice-bran-enriched diet in a crossover trial after a 3-week adaptation period.

  7. 31.SupplementDEX Database: High cholesterolMeta-analysis of the effect of β-glucan intake on blood cholesterol and glucose levels2011

    A meta-analysis of 126 clinical comparisons found ≥3 g/day oat or barley beta-glucan lowered total cholesterol (~0.60 mmol/L) and LDL (~0.66 mmol/L); effects on blood glucose were inconclusive due to high heterogeneity.

  8. 32.SupplementDEX Database: High cholesterolβ-glucan from barley and its lipid-lowering capacity: a meta-analysis of randomized, controlled trials2010

    A meta-analysis of 11 barley trials found barley and barley beta-glucan lowered total cholesterol by 0.30 mmol/L and LDL by 0.27 mmol/L versus control.

  9. 33.SupplementDEX Database: High cholesterolPhysicochemical properties of oat β-glucan influence its ability to reduce serum LDL cholesterol in humans: a randomized clinical trial2010

    In 345 adults, 4 weeks of 3 g/day high- or medium-molecular-weight oat beta-glucan cereal lowered LDL by ~0.19–0.26 mmol/L (~5–6.5%) versus wheat fiber; low-MW beta-glucan (210,000 g/mol) was ineffective.

  10. 34.SupplementDEX Database: High cholesterolThe effects of barley-derived soluble fiber on serum lipids2009

    A meta-analysis of 8 barley trials (391 patients, 4–12 weeks) found barley significantly lowered total cholesterol by 13.4 mg/dL, LDL by 10.0 mg/dL, and triglycerides by 11.8 mg/dL.

  11. 35.SupplementDEX Database: High cholesterolConcentrated oat beta-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial2007

    In 75 hypercholesterolemic adults, 6 g/day concentrated oat beta-glucan for 6 weeks reduced total and LDL cholesterol from baseline, with significantly greater LDL reduction versus dextrose control (p=0.03).

  12. 36.SupplementDEX Database: High cholesterolOat-derived beta-glucan significantly improves HDLC and diminishes LDLC and non-HDL cholesterol in overweight individuals with mild hypercholesterolemia2007

    In 38 overweight hypercholesterolemic men, 8 weeks of bread with 6 g beta-glucan raised HDL by 28%, lowered LDL by 27%, and reduced total cholesterol more than AHA Step II diet alone.

  13. 37.SupplementDEX Database: High cholesterolRandomized controlled crossover study of the effect of a highly beta-glucan-enriched barley on cardiovascular disease risk factors in mildly hypercholesterolemic men2003

    In 18 mildly hyperlipidemic men, 4 weeks of beta-glucan-enriched barley (8–12 g/day) did not significantly change total, LDL, or HDL cholesterol or fasting or postprandial glucose versus glucose control.

  14. 38.SupplementDEX Database: High cholesterolCholesterol-lowering effect of beta-glucan from oat bran in mildly hypercholesterolemic subjects may decrease when beta-glucan is incorporated into bread and cookies2003

    In mildly hypercholesterolemic subjects, 5 g/day beta-glucan in orange juice lowered LDL by 0.26 mmol/L (6.7%) over 2 weeks, but beta-glucan in bread and cookies for 3 weeks did not significantly change LDL.

  15. 39.SupplementDEX Database: High cholesterolModest doses (3 g/day for 8 weeks) of beta-glucan do not reduce concentrations of potentially atherogenic lipoproteins2000

    In 62 adults with mild hyperlipidemia, 3 g/day beta-glucan from oat bran concentrate for 8 weeks did not significantly lower total or LDL cholesterol versus wheat bran control.

  16. 40.SupplementDEX Database: High cholesterolPlasma lipid changes after supplementation with beta-glucan fiber from yeast1999

    In 15 obese hypercholesterolemic men, 15 g/day yeast beta-glucan for 8 weeks significantly lowered total cholesterol by 6–8% at weeks 7–8; LDL fell 8% at week 8 without surviving Bonferroni correction.

  17. 41.SupplementDEX Database: High cholesterolA controlled study on the effect of beta-glucan-rich oat bran on serum lipids in hypercholesterolemic subjects: relation to apolipoprotein E phenotype1992

    In 36 hypercholesterolemic adults, 10.3 g/day beta-glucan from oat bran lowered total and LDL cholesterol at 4 weeks in compliant apoE 3/3 subjects, but values were not significantly below baseline at 8 weeks.

  1. 42.SupplementDEX Database: FatigueEffects of β-glucans on fatigue: a systematic review and meta-analysis2025

    A meta-analysis of 16 RCTs (1,449 participants) found beta-glucan significantly reduced fatigue (SMD −0.32), increased vigor (SMD 0.46), and improved mood (SMD 0.32) versus placebo in healthy adults.

  1. 43.SupplementDEX Database: ObesityRegular Consumption of Green Coffee Phenol, Oat β-Glucan and Green Coffee Phenol/Oat β-Glucan Supplements Does Not Change Body Composition in Subjects with Overweight and Obesity2022

    In 29 overweight/obese adults in a crossover trial, 8 weeks of green coffee phenols (300 mg), oat beta-glucan (2.5 g), or both twice daily did not change body weight, body fat, or circumferences without dietary changes.

  2. 44.SupplementDEX Database: ObesityEffects of cereal beta-glucan consumption on body weight, body mass index, waist circumference and total energy intake: A meta-analysis of randomized controlled trials2019

    A meta-analysis of 20 RCTs found cereal beta-glucan modestly reduced body weight (−0.77 kg) and BMI (−0.62 kg/m²) but did not significantly affect waist circumference or energy intake.

  3. 45.SupplementDEX Database: ObesityYeast β-Glucan Modulates Inflammation and Waist Circumference in Overweight and Obese Subjects2017

    In 44 overweight/obese adults, 477 mg/day yeast beta-glucan for 6 weeks reduced waist circumference and blood pressure, raised IL-10, and lowered IL-6 and TNF-α versus placebo.

  4. 46.SupplementDEX Database: ObesityEffects of high β-glucan barley on visceral fat obesity in Japanese individuals: A randomized, double-blind study2017

    In 100 Japanese adults with central obesity, 12 weeks of high beta-glucan barley (4.4 g/day) reduced body weight, BMI, and visceral fat area, with greater VFA reduction in those with VFA ≥100 cm².

  5. 47.SupplementDEX Database: ObesityOat beta-glucan supplementation does not enhance the effectiveness of an energy-restricted diet in overweight women2010

    In 66 overweight women on energy-deficit diets, adding 5–9 g/day oat beta-glucan for 3 months did not enhance weight loss or metabolic improvements beyond diet alone.

  1. 48.SupplementDEX Database: Upper respiratory tract infectionEffects of Chronic Barley Consumption on Upper Respiratory Tract Symptoms in Japanese Healthy Adults: A Randomized, Parallel-Group, Controlled Trial2024

    A randomized, parallel-group controlled trial in healthy Japanese adults found that daily consumption of cooked waxy barley (containing ~1.8 g β-(1,3/1,4)-glucan) for 8 weeks reduced cumulative days of sneezing and fatigue, and lessened severity of nasal symptoms and tension compared with white rice.

  2. 49.SupplementDEX Database: Upper respiratory tract infectionEffects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis2021

    A meta-analysis of 13 RCTs found yeast beta-glucan significantly reduced URTI incidence (OR 0.35), episode count (SMD −0.32), and duration (SMD −0.31) versus placebo in healthy subjects.

  1. 50.SupplementDEX Database: Atopic dermatitis (eczema)β-Glucan-based cream (containing pleuran isolated from Pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis2016

    In 80 of 105 mild-to-moderate atopic dermatitis patients completing a split-body study, topical beta-glucan (pleuran) cream significantly reduced EASI scores and pruritus on the treated side versus control.

  1. 51.SupplementDEX Database: Canker soresThe effect of beta-glucan on recurrent aphthous stomatitis2009

    A randomized controlled trial of oral beta-glucan for recurrent aphthous stomatitis was identified, but available abstract text was insufficient to report specific outcomes.

  1. 52.SupplementDEX Database: Exercise-induced respiratory infectionsBeverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial2020

    In marathon runners, per-protocol analysis found 250 mg/day yeast beta-glucan for 91 days reduced URTI symptomatic days (3.43 vs 3.84), symptom severity, and missed workout days versus control, without fewer URTI episodes.

  2. 53.SupplementDEX Database: Exercise-induced respiratory infectionsBaker’s yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise2013

    In athletes, 250 mg/day baker's yeast beta-glucan for 10 days reduced post-exercise cold/flu symptom days by 37% and increased salivary IgA by 32% at 2 h post-exercise versus placebo.

  3. 54.SupplementDEX Database: Exercise-induced respiratory infectionsPleuran (β-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes2011

    In 50 athletes, 3 months of pleuran (mushroom beta-glucan) reduced URTI symptoms, increased NK cells, and maintained phagocytosis versus placebo, where phagocytosis declined.

  4. 55.SupplementDEX Database: Exercise-induced respiratory infectionsEffect of BETA 1,3/1,6 GLUCAN on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes2009

    In 75 marathon runners, 250–500 mg/day beta-1,3/1,6 glucan for 4 weeks post-marathon reduced URTI symptoms and improved mood (less fatigue, tension, anger; more vigor) versus placebo.

  5. 56.SupplementDEX Database: Exercise-induced respiratory infectionsBeta-glucan, immune function, and upper respiratory tract infections in athletes2008

    In 36 trained male cyclists, 5.6 g/day oat beta-glucan for 18 days did not alter resting or exercise-induced immune markers or URTI incidence after 3 h/day cycling for 3 days.

  1. 57.SupplementDEX Database: Hypertension (High blood pressure)Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress in men and women with elevated blood pressure2007

    In 97 adults with elevated blood pressure, 12 weeks of oat beta-glucan foods improved post-meal insulin responses versus control; in obese participants (BMI >31.5), systolic BP fell 8.3 mmHg and diastolic 3.9 mmHg.

  2. 58.SupplementDEX Database: Hypertension (High blood pressure)Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial2002

    In 18 hypertensive, hyperinsulinemic adults, 6 weeks of oat cereal (5.52 g/day beta-glucan) reduced systolic BP by 7.5 mmHg and diastolic by 5.5 mmHg versus low-fiber cereal, and lowered total cholesterol by 9% and LDL by 14%.

  3. 59.SupplementDEX Database: Hypertension (High blood pressure)Acute effects of oats and vitamin E on endothelial responses to ingested fat2001

    In 50 healthy adults, consuming oatmeal with 3 g beta-glucan before a high-fat meal prevented the 13.4% decline in brachial artery flow seen with wheat cereal; vitamin E had a similar protective effect.

  1. 60.SupplementDEX Database: Inflammatory bowel disease (IBD)Beta-glucan, inositol and digestive enzymes improve quality of life of patients with inflammatory bowel disease and irritable bowel syndrome2017

    In 43 IBD patients in remission with IBS symptoms, 4 weeks of beta-glucan, inositol, and digestive enzymes plus mesalamine reduced abdominal pain, bloating, and flatulence and improved well-being versus mesalamine alone.

  1. 61.SupplementDEX Database: Irritable bowel syndrome (IBS)Effect of beta-glucan, inositol and digestive enzymes in GI symptoms of patients with IBS2011

    In 50 IBS patients, Biointol (beta-glucan, inositol, digestive enzymes) significantly improved bloating, flatulence, and abdominal pain versus no treatment, but did not improve other IBS symptoms.

  1. 62.SupplementDEX Database: Lower respiratory tract infectionsPrimary care experience on Stimunex® gocce in children with recurrent respiratory infections: a real-world study during the COVID-19 pandemic era2022

    In 298 children with recurrent respiratory infections, 4 months of Stimunex (Sambucus, beta-glucan, zinc, vitamin D) versus standard care reduced infection number and duration and was well tolerated during the COVID-19 pandemic.

  1. 63.SupplementDEX Database: Postoperative painImpact of beta-glucan on the faecal microbiota of polypectomized patients: a pilot study2011

    In polypectomized adults, 3 months of 3 g/day barley beta-glucan in bread altered coliform counts and short-chain fatty acid ratios and reduced bloating/abdominal pain versus placebo, without major microbiota shifts.

  1. 64.SupplementDEX Database: Stretch marks (striae distensae)Improving the outcome of treating striae gravidarum by combined therapies using topical β-glucan and 1565-nm non-ablative fractional laser: A prospective randomized vehicle-controlled parallel group study2022

    In 56 postpartum women, 12 weeks of topical beta-glucan mildly improved striae gravidarum appearance; non-ablative fractional laser showed greater benefit, and combined laser plus beta-glucan further improved atrophy versus laser plus vehicle.

On this page