Fractures
Supplements studied for fractures.
Overview
Vitamin D plus calcium (DEX Score 56; low effect size, very high evidence, medium trust; 19 studies)) may lower hip and non-spine fracture risk by about 20–25% in older adults when combined (~800 IU vitamin D with calcium), though vitamin D alone usually does not prevent fractures without osteoporosis.
Calcium supplements alone (DEX Score 56, 17 studies) did not reliably reduce fracture risk in large long-term trials such as the Women's Health Initiative, despite slight bone strength changes. Vitex agnus-castus, Green Tea, and Lutein show little or only observational fracture data. See the heatmap and evidence reviews below.
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Relevant supplements sorted by DEX Score.
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SupplementDEX Database
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