SupplementDEX

Fatigue

Supplements studied for fatigue.

Overview

Fatigue has several reviewed supplements with varying strength. Panax Ginseng (DEX Score 68; medium effect size, very high evidence, medium trust; 11 studies) and Rhodiola (DEX Score 68; medium effect size, high evidence, high trust) have medium evidence for reducing fatigue in chronic fatigue and stressful settings, though ginseng results are inconsistent and placebo effects may be strong.

Iron (DEX Score 72; medium effect size, high evidence, very high trust) moderately reduces tiredness in adults with low iron without anemia over 4–12 weeks. Beta-Glucan (DEX Score 64; medium effect size, medium evidence, high trust) lacks a detailed summary. Quercetin (DEX Score 32; very low effect size, low evidence, medium trust) showed no meaningful benefit. See the heatmap and evidence reviews below for all 11 supplements.

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SupplementDEX Database

11 supplements for , and rated at least stars. All purchase bands. No minimum star filter.

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