Erythropoietic protoporphyria (EPP)
Supplements studied for erythropoietic protoporphyria (EPP).
Overview
Erythropoietic protoporphyria (EPP) has one reviewed supplement: N-Acetyl Cysteine (NAC) (DEX Score 44; low effect size, low evidence, medium trust). Small trials testing oral NAC 1800 mg daily for four weeks did not reduce light sensitivity in people with EPP compared with control conditions in the available research.
No beneficial supplement signal appears for EPP, and both summarized studies reported null outcomes for the primary symptom. See the heatmap and evidence reviews below for ratings and trial summaries.
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