Elderly physical function

Overview

SupplementDEX lists 2 supplements studied for elderly physical function across 2 trials. The strongest indexed signals include Flaxseed Oil, Vitamin B9. See the heatmap and evidence reviews below for full ratings across all supplements.

Effect graph

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Relevant supplements

Relevant supplements sorted by DEX Score.


Flaxseed Oil	★★★★★	Low
Vitamin B9 (Folate)	★★★★★	Very Low / None

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Studies

Find individual evidence reviews for supplements sorted by DEX Score.

2 supplements for and rated at least stars. All purchase bands. No minimum star filter.

Flaxseed OilView supplement →

Reconsider purchase★★★★★

How we scored this

Effect SizeLowEvidenceLowTrustMedium

Evidence Review

Early research suggests flaxseed-oil-related omega-3s may help some aspects of strength or physical function in older adults when combined with resistance training, but the evidence is still limited.
More research is needed to know how reliable the benefit is.

Browse 1 study

RCTAlpha-linolenic acid supplementation and resistance training in older adults2009

In 51 older adults resistance training 12 weeks, flax oil ~14 g/day ALA lowered IL-6 in men and combined with training improved strength, lean mass, and bone density versus placebo.

Effect: Benefit
Duration: 12 weeks
Dose: 14 g/day
Population: Older adults
Avg age: ~65

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Vitamin B9 (Folate)View supplement →

Do not purchase★★★★★

How we scored this

Effect SizeVery Low / NoneEvidenceLowTrustMedium

Evidence Review

In older adults, taking folic acid with vitamin B12 for two years did not clearly improve strength, physical performance, or reduce problems related to falling.
The overall benefit appears minimal.

Browse 1 study

RCTA Randomized Controlled Trial to Examine the Effect of 2-Year Vitamin B12 and Folic Acid Supplementation on Physical Performance, Strength, and Falling: Additional Findings from the B-PROOF Study2016n=2,919

A randomized trial of 2919 older adults found that 600 IU/day for 2 years moreover, time to first fall was not significantly different (HR: 1.0, 95% CI 0.9-1.2).

Effect: No Benefit
Duration: 2 years
Dose: 600 IU/day
Population: Older adults
Participants: 2,919
Ages: 65+

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Evidence visualised

Same ratings as above, aggregated so you can see coverage and imbalance.

Purchase-guidance distribution

How many supplements fall in each purchase band

Effect-size distribution

How large the reported benefits tend to be

Study distribution across 2 supplements for elderly physical function (2 studies total).
Supplement	DEX	Studies	Meta-analyses	Share
Flaxseed Oil	★★★★★44%	1	0	50%
Vitamin B9 (Folate)	★★★★★32%	1	0	50%

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Elderly physical function

Overview

Effect graph

Relevant supplements

Studies

Evidence visualised

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