Lead Exposure

Overview

In workers exposed to lead, taking N-Acetyl Cysteine (NAC) daily for 12 weeks lowered blood lead levels and reduced oxidative stress in blood cells in one study. Evidence remains limited to this single low-rated trial with no broader confirmation.

See the evidence review below for details on this research.

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N-Acetyl Cysteine (NAC)	★★★★★	Low

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Studies

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N-Acetyl Cysteine (NAC)View supplement →

Reconsider purchase★★★★★

How we scored this

Effect SizeLowEvidenceLowTrustMedium

Evidence Review

A study of workers exposed to lead found that taking N-acetylcysteine (NAC) daily for 12 weeks lowered their blood lead levels and reduced oxidative stress in their blood cells.

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RCTThe administration of N-acetylcysteine reduces oxidative stress and regulates glutathione metabolism in the blood cells of workers exposed to lead2013n=49

A 12-week RCT of 171 lead-exposed workers found NAC (200 mg/day) reduced blood lead levels and restored erythrocyte glutathione versus untreated controls.

Effect: Benefit
Duration: 12 weeks
Dose: 200 mg/day
Population: ALL patients
Participants: 49

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Effect-size distribution

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Study distribution across 1 supplements for lead exposure (1 studies total).
Supplement	DEX	Studies	Meta-analyses	Share
N-Acetyl Cysteine (NAC)	★★★★★44%	1	0	100%

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Overview

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Studies

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