SupplementDEX

Yerba Mate

Yerba mate is a caffeinated South American tea studied for energy, metabolic, and cognitive outcomes.

Overview

What is yerba mate?

Yerba mate is a tea made from the leaves of the Ilex paraguariensis plant. It contains biologically active compounds including caffeine, chlorogenic acid, theobromine and other flavonoids, xanthins, cinnamic acids, saponins, minerals and vitamins.

Dosage

Typical dosing unknown.

Effect graph

Effect heatmap

SupplementDEX Database

13 conditions for , and rated at least stars. All purchase bands. No minimum star filter.

Database Snapshot

Studies per condition
Yerba Mate evidence base by condition

Most yerba mate research is concentrated in a handful of conditions.

  • Obesity accounts for 7 of 24 studies (29%).
  • Dyslipidemia accounts for 4 of 24 studies (17%).
  • Cancer risk accounts for 2 of 24 studies (8%).
  • Sparse coverage remains for Cancer risk, Osteoporosis, Athletic performance.
Studies per year
Yerba Mate publications over time

Safety

Dose windows

Long-term

Yerba mate consumption is associated with an increased risk of cancer of many types including stomach, kidney, bladder, cervical and mouth cancer. Although, this increased risk may be attributed to the high temperatures at which yerba mate is often consumed, at least in cases of oesophageal cancer.

Frequently Asked Questions

References

Sources20 references

SupplementDEX uses only high-quality sources to determine supplement effectiveness.

  1. 1.SupplementDEX Database: DyslipidemiaEffect of Yerba Mate (Ilex paraguariensis) on Lipid Levels: A Systematic Review and Meta-Analysis2022

    In a meta-analysis of 378 participants, in conclusion, this research showed that yerba mate consumption was not associated with a significant change in lipid levels.

  2. 2.SupplementDEX Database: DyslipidemiaAssociation of mate tea (Ilex paraguariensis) intake and dietary intervention and effects on oxidative stress biomarkers of dyslipidemic subjects2011

    In an RCT in patients, for all groups, there was a significant increase in ferric reducing antioxidant potential and reduced glutathione concentrations but no significant changes in LOOH, protein carbonyl, and paraoxonase-1 values.

  3. 3.SupplementDEX Database: DyslipidemiaMate tea (Ilex paraguariensis) improves glycemic and lipid profiles of type 2 diabetes and pre-diabetes individuals: a pilot study2011

    In an RCT, 330 mL mate tea, 3×/day, for 60 days, mate tea consumption decreased significantly the levels of fasting glucose (25.0 mg/dL), glycated hemoglobin A(1c) (HbA(1c)) (0.85%), and low-density lipoprotein cholesterol (LDL-c) (13.5 mg/dL) of T2DM subjects (p < 0.05); however, it did not change the intake of total energy, protein,...

  4. 4.SupplementDEX Database: DyslipidemiaConsumption of yerba mate ( Ilex paraguariensis ) improves serum lipid parameters in healthy dyslipidemic subjects and provides an additional LDL-cholesterol reduction in individuals on statin therapy2009

    In a controlled trial of 57 participants, for 40 days, it was thus concluded that intake of yerba mate infusion improved the lipid parameters in normolipidemic and dyslipidemic subjects and provided an additional LDL-cholesterol reduction in hypercholesterolemic subjects on statin treatment, which may reduce the risk for...

  1. 5.SupplementDEX Database: Athletic performanceMetabolic and Performance Effects of Yerba Mate on Well-trained Cyclists2017

    In an RCT of 9 participants, 5 g/day, respiratory exchange ratio during TT indicated carbohydrate dependence and did not differ between treatments (PL, 0.95 ± 0.03 (SD); YM, 0.95 ± 0.02).

  1. 6.SupplementDEX Database: Bone mineral densityYerba Mate (Ilex paraguariensis) consumption is associated with higher bone mineral density in postmenopausal women2011

    In an observational study of 146 participants, ≥1 L yerba mate tea/day, from a program for osteoporosis prevention and treatment, postmenopausal women who drank at least 1 L of Yerba Mate tea daily during 4 or more years (n=146) were identified, and matched by age and time since menopause with an equal number of women who did not...

  1. 7.SupplementDEX Database: Cancer riskMaté consumption association with upper aerodigestive tract cancers: A systematic review and meta-analysis2018

    In a meta-analysis, consumption of more than one liter of maté per day was associated with increased odds of having UADT cancer compared to an intake of less than one liter per day (OR = 1.72; 95%CI = 1.47-2.01).

  2. 8.SupplementDEX Database: Cancer riskDrinking of maté and the risk of cancers of the upper aerodigestive tract in Latin America: a case-control study2010

    In an observational study, our study strengthens the evidence of an association between maté drinking and esophageal cancer; the hypothesis of an association with other UADT cancers remains to be clarified.

Cognitive performance

1 reference
  1. 9.Psychological and cardiovascular effects of Guaraná and yerba mate: A comparison with coffee. See external sourceExternal source
  1. 10.SupplementDEX Database: Metabolic healthEffects of mate tea (Ilex paraguariensis) ingestion on mRNA expression of antioxidant enzymes, lipid peroxidation, and total antioxidant status in healthy young women2009

    In a study in women, these results suggest that regular consumption of mate tea may increase antioxidant defense of the body by multiple mechanisms.

  1. 11.SupplementDEX Database: Muscle mass & strengthAcute Supplementation of Yerba Mate Extract Did Not Change Muscle Strength in Physically Active Men Following the Strength Muscle Test: A Pilot Clinical Trial2022

    In an RCT of 12 participants, placebo: 59.5 ± 21.5 kg, p = 1.000, Cohen's d = 0.) In conclusion, acute intake of YM did not change muscle strength in physically active men.

  1. 12.SupplementDEX Database: OsteoporosisThe yerba mate intake has a neutral effect on bone: A case-control study in postmenopausal women2018

    In an observational study of 46 participants, in conclusion, the yerba mate intake is not associated with fracture, and it appears to have a neutral effect on the bone metabolism.

  1. 14.SupplementDEX Database: ObesityHeavy drinkers of Ilex paraguariensis beverages show lower lipid profiles but higher body weight2018

    In an observational study of 18 participants, induced hypoglycemia and compensatory higher intake of refined carbohydrates may represent a possible cause.

  2. 16.SupplementDEX Database: ObesityAnti-obesity effects of Yerba Mate (Ilex Paraguariensis): a randomized, double-blind, placebo-controlled clinical trial2015

    In an RCT of 15 participants, 3 g/day, for 12 weeks, these results suggested that Yerba Mate supplementation may be effective for treating obese individuals.

  3. 17.SupplementDEX Database: ObesityYerba Maté (Illex Paraguariensis) ingestion augments fat oxidation and energy expenditure during exercise at various submaximal intensities2014

    In an RCT in obese patients, 1,000 mg yerba mate, yM significantly increased FAO and EEFAO by 24% in all submaximal exercise intensities below 70% of [Formula: see text] (p < 0.001, ANOVA main effects) with post hoc tests showing a higher FAO and EEFAO (p < 0.05) at the lower exercise intensities (e.g.

  4. 18.SupplementDEX Database: ObesityWeight loss and delayed gastric emptying following a South American herbal preparation in overweight patients2001

    In 22 overweight patients, the herbal blend YGD (yerba mate, guarana, damiana) delayed gastric emptying and reduced body weight over 45 days versus placebo.

  5. 19.SupplementDEX Database: ObesityThermogenic effects of commercially available plant preparations aimed at treating human obesity1999

    In an RCT in obese patients, no significant increase in energy expenditure (EE) has been noted after treatment with any of these preparations.

  6. 13.Efficacy of Ilex paraguariensis versus Placebo on Lipid Profile in Randomized Clinical Trial: A Systematic Review and Meta-analysis. See external sourceExternal source
  7. 15.The Effect of Maté Extract on Body Weight and Fat Reduction in Obese Women: A Randomized Placebo-controlled Clinical Trial. See external sourceExternal source
  1. 20.SupplementDEX Database: Parkinson's diseaseA Case-Control Study of the Effects of Chimarrão (Ilex paraguariensis) and Coffee on Parkinson's Disease2021

    In an observational study of 200 participants, Chimarrão consumption was inversely associated with PD, even after adjusting for coffee intake, suggesting a possible protective role.

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