Transurethral resection of the prostate (TURP)

Overview

Saw Palmetto is the only supplement studied before transurethral resection of the prostate (TURP), with medium-level evidence from three trials. Taking 320 mg daily for two months before surgery may improve outcomes, including reduced blood loss, shorter surgery time, fewer complications, less catheter use, and shorter hospital stays. A lower dose of 160 mg daily for five weeks did not show these benefits.

Saw Palmetto carries medium effect-size, evidence, and trust ratings. See the heatmap and evidence reviews below for trial details.

Effect graph

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Saw Palmetto	★★★★★	Medium

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Studies

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Saw PalmettoView supplement →

Consider purchase★★★★★

How we scored this

Effect SizeMediumEvidenceMediumTrustHigh

Evidence Review

Taking saw palmetto at 320 mg daily before prostate surgery (TURP) may improve surgery outcomes.
Studies found that taking this higher dose for 2 months before surgery reduced blood loss, surgery time, complications, catheter use, and hospital stay.
But taking a lower dose (160 mg daily for 5 weeks) did not show these benefits.

Browse 3 studies

RCTSerenoa repens (Permixon®) reduces intra- and postoperative complications of surgical treatments of benign prostatic hyperplasia2010n=144

In 120 BPH patients before prostate surgery, 2 months of Permixon 320 mg/day shortened operative time, reduced bleeding and transfusion needs, and shortened catheterization versus no pretreatment.

Effect: Benefit
Dose: 320 mg/day
Population: Patients with BPH
Participants: 144

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RCTEffects of short-term dutasteride and Serenoa repens on perioperative bleeding and microvessel density in patients undergoing transurethral resection of the prostate2009n=27

In 75 men before TURP, 5 weeks of dutasteride reduced intraoperative bleeding and prostatic microvessel density versus control, while Serenoa repens 160 mg/day did not.

Effect: No Benefit
Duration: 5 weeks
Dose: 160 mg/day
Population: Patients with benign prostatic hyperplasia
Participants: 27

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RCTEfficacy of pretreatment with Serenoa repens on bleeding associated with transurethral resection of prostate2004n=108

In 88 BPH patients before TURP, at least 8 weeks of Permixon 320 mg/day reduced perioperative bleeding (124 vs 287 mL) and shortened catheterization versus no pretreatment.

Effect: Benefit
Duration: 8 weeks
Dose: 320 mg/day
Population: Patients with benign prostatic hyperplasia
Participants: 108

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Evidence visualised

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Effect-size distribution

How large the reported benefits tend to be

Study distribution across 1 supplements for transurethral resection of the prostate (turp) (3 studies total).
Supplement	DEX	Studies	Meta-analyses	Share
Saw Palmetto	★★★★★64%	3	0	100%

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Transurethral resection of the prostate (TURP)

Overview

Effect graph

Relevant supplements

Studies

Evidence visualised

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