Tardive dyskinesia
Supplements studied for tardive dyskinesia.
Overview
Several supplements have been studied for tardive dyskinesia in people taking antipsychotic drugs, with some showing medium-level evidence. Vitamin E may slow symptom worsening rather than improve symptoms outright, especially at higher doses when symptoms began within five years. Branched Chain Amino Acids (BCAAs) reduced movement symptoms by 30–60% over three weeks in studies of adults and children. Ginkgo extract (EGb 761) at 80 mg three times daily for 12 weeks also reduced symptoms in one trial.
Melatonin and Lecithin carry low ratings. Melatonin showed mixed results across small studies, and lecithin did not outperform placebo. See the heatmap and evidence reviews below for evidence across five supplements.
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