SupplementDEX

Osteoarthritis

Supplements studied for osteoarthritis.

Overview

Several supplements show medium-strength evidence for osteoarthritis. Curcumin (DEX Score 68; medium effect size, very high evidence, medium trust; 35 studies) may reduce knee pain and stiffness and decrease pain-medication use, though effects vary by product and population. Boswellia (DEX Score 68; medium effect size, very high evidence, medium trust) and Ginger (DEX Score 68; medium effect size, very high evidence, medium trust) may lessen joint pain, especially in knee or hip OA. SAMe (DEX Score 68; medium effect size, very high evidence, medium trust) may reduce pain and improve function at doses of 400–1200 mg daily, with effects comparable to some NSAIDs over time.

Devil's Claw (DEX Score 68; medium effect size, high evidence, high trust) is listed with medium ratings but no detailed summary is available. See the heatmap and evidence reviews below for product-level comparisons.

Effect graph

Subscribe to access all content

Interactive visualisations of ranked conditions and clinical benefit with purchase guidance.

Get started for free

Already a subscriber? Sign in

Relevant supplements heatmap

Relevant supplements sorted by DEX Score.

Subscribe to access all content

See effect size, evidence strength, and trust at a glance for every condition.

Get started for free

Already a subscriber? Sign in

SupplementDEX Database

26 supplements for , and rated at least stars. All purchase bands. No minimum star filter.

Subscribe to access all content

Read this and 2,600+ other evidence reviews on our practitioner plan.

Get started for free

Already a subscriber? Sign in

Evidence visualised

Subscribe to view condition evidence

Visual summaries of supplement evidence ranked by condition.

Get started for free

Already a subscriber? Sign in

On this page