Intermittent claudication
Supplements studied for intermittent claudication.
Overview
Three supplements are indexed for intermittent claudication (6 studies). Ginkgo (DEX Score 72; medium effect size, high evidence, very high trust; 3 studies) may help people with leg circulation problems walk without pain, though the effect is usually small and it should not replace standard medical treatments.
L-Carnitine shares the same medium ratings (DEX Score 56; 2 studies) but there is not enough evidence to determine benefit. Caffeine (DEX Score 44; low effect size, low evidence, medium trust; 1 study) has unknown usefulness. See the evidence reviews below for trial comparisons.
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