Rett syndrome
Supplements studied for rett syndrome.
Overview
L-Carnitine (2 small studies) is the only supplement studied for Rett syndrome. Trials in children suggest that L-carnitine at about 100 mg per kg of body weight daily, split into two to three doses for up to six months, may modestly improve well-being, movement skills, sleep quality, and communication compared with no treatment or placebo.
Evidence remains limited to small studies without robust confirmation. See the heatmap and evidence reviews below.
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