SupplementDEX

Wrinkles

Supplements studied for wrinkles.

Overview

Topical Vitamin C carries the strongest evidence for wrinkles, with medium ratings across five studies. Creams or serums with 3–10% vitamin C used for three months or more may reduce wrinkles and improve skin firmness and smoothness, especially when combined with vitamin E or retinol.

Vitamin A (8 studies) and Nattokinase are also indexed for skin wrinkles. Green Tea, Ashwagandha, Panax Ginseng, and Tyrosine carry low ratings with mixed or preliminary results. See the heatmap and evidence reviews below.

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SupplementDEX Database

7 supplements for , and rated at least stars. All purchase bands. No minimum star filter.

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